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Question 1 of 2
What percentage of patients with myelofibrosis will become anemic within the first year of diagnosis?
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The MPN Hub was pleased to speak to Aaron Gerds, Cleveland Clinic Taussig Cancer Institute, Cleveland, US. We asked, How might luspatercept benefit patients with myelofibrosis (MF)?
How might luspatercept benefit patients with myelofibrosis?
Aaron Gerds opens by discussing the prevalence and issue of anemia in patients with MF, noting that almost all patients will become anemic at some point in the course of their disease. Gerds discusses luspatercept as a treatment option in this indication, sharing the latest clinical trial data from the phase II ACE-536-MF-001 study of luspatercept for the treatment of anemia in patients with myelofibrosis; emphasizing the benefit of a reduction in transfusion dependency for patients treated with luspatercept. This interview closes with a look to ongoing clinical trials, including the INDEPENDENCE (NCT04717414) study and the implications of these data on future management strategies for anemic myelofibrosis.
During the interview Gerds made the following key points:
Listen to the interview as a podcast
How might luspatercept benefit patients with myelofibrosis?
Your opinion matters
As a result of this content, I commit to reviewing the latest data with luspatercept to guide my treatment of myelofibrosis-associated anemia.
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References
Your opinion matters
On average, how many patients with myelofibrosis do you see in a month?