Find all the latest information in myeloproliferative neoplasms, arranged by types, translocations, and mutations. Listed below are recently updated categories.
Molecular mechanisms associated with leukemic transformation of PV and ET
Leukemic transformation in patients with polycythemia vera (PV) and essential thrombocythemia (ET) is considered a leading...
Underlying mechanisms in the genetic disposition of myeloproliferative neoplasms
Somatic driver mutations are known to exhibit a role as main promoters in myeloproliferative neoplasms (MPN)...
Predicting transition in prefibrotic myelofibrosis
With the 2016 revision to the World Health Organization classification of myeloproliferative neoplasms (MPN), patients with prefibrotic primary...
Applying prognostic models for myelofibrosis in practice
The review by How et al. covers established and emerging prognostic models for PMF.
The practical use of myelofibrosis genomics in a clinical setting
Myelofibrosis (MF), a subtype of the Philadelphia chromosome-negative myeloproliferative neoplasms (MPN), is characterized by Janus...
Understanding the pathology of MPN: The value of in vivo and in vitro models
Among chronic Philadelphia-negative myeloproliferative neoplasms (MPN), polycythemia vera (PV) is considered the most...
The long-term efficacy of interferon alpha in targeting different driver mutations involved in MPN
Mutations in JAK2V617F, calreticulin (CALR), and thrombopoietin receptor (MPL) genes are three main...
Curative role of allogeneic hematopoietic stem cell transplantation in patients with myeloproliferative neoplasm, unclassifiable
Myeloproliferative neoplasm, unclassifiable (MPN-U) is a heterogeneous...
Epigenetic modifier mutations
JAK2 driver mutations
JAK2 exon 12 deletions
JAK2 exon 12 insertions
MPL driver mutations
Chronic eosinophilic leukemia
Chronic neutrophilic leukemia
Tumor suppressor mutations