Comparison of gene expression profiles in MPN subtypes

Myeloproliferative neoplasms (MPN) are known to be heterogeneous disorders that have the potential to progress over time. Essential...

FDA biologics license application of ropeginterferon alfa-2b resubmitted for the treatment of PV

Polycythemia vera (PV) is a subtype of myeloproliferative neoplasms, characterized by excessive red...

Reconstruction of cancer cell lineage history in patients with MPN

The JAK2 V617F mutation is common in the majority of Philadelphia chromosome-negative myeloproliferative neoplasms (MPN), where the...

Givinostat in polycythemia vera: Long-term safety and efficacy

Polycythemia vera (PV) is a BCR-ABL1-negative subtype of myeloproliferative neoplasms (MPN), characterized by excessive erythroid...

The safety and efficacy of the four JAK inhibitors in patients with myelofibrosis

The approval of ruxolitinib for the treatment of myeloproliferative neoplasms (MPN) has been transformative. Newer...

Survival outcomes of fedratinib for patients with myelofibrosis: JAKARTA and JAKARTA2 trials

During the 26th Congress of the European Hematology Association (EHA2021), the MPN Hub Steering Committee...

Allogeneic hematopoietic stem cell transplantation for myelofibrosis

Primary myelofibrosis (MF) is a type of myeloproliferative neoplasm (MPN) characterized by cytopenia, and splenomegaly, and can...

Interim translational data from the MANIFEST phase II study of pelabresib in myelofibrosis

Myelofibrosis (MF) is characterized by abnormal megakaryopoiesis and overproduction of proinflammatory...

EPICOVIDEHA registry: Epidemiology and outcomes in patients with hematologic malignancies infected with COVID-19

Patients with hematologic malignancies (HMs) may have intensified immune dysregulation...

Survival outcomes of fedratinib for patients with myelofibrosis: JAKARTA and JAKARTA2 trials

During the 26th Congress of the European Hematology Association (EHA2021), the MPN Hub Steering Committee...

Interim translational data from the MANIFEST phase II study of pelabresib in myelofibrosis

Myelofibrosis (MF) is characterized by abnormal megakaryopoiesis and overproduction of proinflammatory...

Fungal superinfections and COVID-19 in the ICU

The COVID-19 pandemic has caused a worldwide healthcare crisis. In addition to the morbidity caused by the initial infection, severely ill patients are...