All content on this site is intended for healthcare professionals only. By acknowledging this message and accessing the information on this website you are confirming that you are a Healthcare Professional. If you are a patient or carer, please visit the MPN Advocates Network.
The mpn Hub website uses a third-party service provided by Google that dynamically translates web content. Translations are machine generated, so may not be an exact or complete translation, and the mpn Hub cannot guarantee the accuracy of translated content. The mpn and its employees will not be liable for any direct, indirect, or consequential damages (even if foreseeable) resulting from use of the Google Translate feature. For further support with Google Translate, visit Google Translate Help.
The MPN Hub is an independent medical education platform, sponsored by AOP Health, GSK, Sumitomo Pharma, and supported through educational grants from Bristol Myers Squibb and Incyte. The funders are allowed no direct influence on our content. The levels of sponsorship listed are reflective of the amount of funding given. View funders.
Now you can support HCPs in making informed decisions for their patients
Your contribution helps us continuously deliver expertly curated content to HCPs worldwide. You will also have the opportunity to make a content suggestion for consideration and receive updates on the impact contributions are making to our content.
Find out more
Create an account and access these new features:
Bookmark content to read later
Select your specific areas of interest
View MPN content recommended for you
How effective are JAK inhibitor combinations for patients with myelofibrosis?
Featured:
Srdan VerstovsekDo you know... In a post hoc analysis of the SIMPLIFY-1 trial, how many patients with moderate anemia at baseline vs severe anemia at baseline, respectively, achieved Hb >10 g/dL by Week 24?
During the 2nd How to Diagnose & Treat CML / MPN, the MPN Hub spoke to Srdan Verstovsek, MD Anderson Cancer Center, Houston, US. We asked, How effective are JAK inhibitor combinations for patients with myelofibrosis?
How effective are JAK inhibitor combinations for patients with myelofibrosis?
JAK inhibitors can control progressive symptomatic splenomegaly and disease-related symptoms; however, they may also worsen anemia in patients with myelofibrosis. Verstovsek outlines JAK inhibitor combinations of luspatercept, CPI-0610, navitoclax, and hypomethylating agents to help manage a wider range of symptoms.
Please indicate your level of agreement with the following statements:
The content was clear and easy to understand
The content addressed the learning objectives
The content was relevant to my practice
I will change my clinical practice as a result of this content