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EHA2023 abstracts: What’s hot in MPN?

By Oscar Williams

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Jun 5, 2023


To help navigate the exciting content being presented at the EHA2023 Congress, the MPN Hub Steering Committee have provided their recommendations for the top abstracts to look out for in MPN.

Friday, June 9, 2023

Abstract

Type

Title

Presenter

S168

Oral presentation

Pelabresib (CPI-0610) monotherapy in patients with high-risk essential thrombocythemia refractory or intolerant to hydroxyurea: Preliminary results from MANIFEST study

Francesco Passamonti 

P1008

Poster presentation

The telomerase inhibitor imetelstat differentially targets JAK2V617F- versus CALR-mutant myeloproliferative neoplasm cells and inhibits JAK-STAT signaling

Nicolas Chatain 

P1027

Poster presentation

Updated durability of response and safety in MANIFEST Arm 3: Pelabresib (CPI-0610) combined with ruxolitinib for JAK inhibitor treatment-naïve patients with myelofibrosis

Claire Harrison

P1032

Poster presentation

Characteristics and clinical outcomes in patients with polycythemia vera receiving ruxolitinib after hydroxyurea: A longitudinal analysis from reveal

Ruben
Mesa

P1044

Poster presentation

Reduction in red blood cell transfusion burden: A novel longitudinal time-dependent analysis in patients with transfusion-dependent myelofibrosis treated with momelotinib

Claire Harrison

P1057

Poster presentation

Indirect treatment comparisons of momelotinib vs pacritinib safety and anemia outcomes in patients with myelofibrosis

Lucia Masarova

P1062

Poster presentation

Indirect treatment comparison of momelotinib vs fedratinib safety in patients with myelofibrosis

Francesca Palandri

Saturday, June 10, 2023

Abstract

Type

Title

Presenter

S210

Oral presentation

An open-label, global, phase 1b/2 study adding navtemadlin (NVTM) to ruxolitinib (RUX) in patients with primary or secondary myelofibrosis who have a suboptimal response to RUX

John Mascarenhas

S211

Oral presentation

Efficacy and safety of ropeginterferon alfa-2b for pre-fibrotic primary myelofibrosis and DIPSS low/intermediate-1 risk myelofibrosis: Updated results and genomic characteristics

Harry Gill 

S212

Oral presentation

A randomized double-blind phase 3 study of jaktinib versus hydroxyurea in patients with intermediate-2 or high risk myelofibrosis

Yi Zhang

S213

Oral presentation

BMS-986158, a potent BET inhibitor, as monotherapy and in combination with ruxolitinib or fedratinib in intermediate- or high-risk myelofibrosis: Results from a phase 1/2 study

Haifa Kathrin
Al-Ali

Sunday, June 11, 2023

Abstract

Type

Title

Presenter

LB2710

Late breaking oral presentation

Targeted therapy of uncontrolled erythrocytosis in polycythemia vera with the hepcidin mimetic, rusfertide: Blinded randomized withdrawal results of the REVIVE study

Marina Kremyanskaya

 

EHA 2023 top abstracts

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