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During the last steering committee (SC) meeting that was held on April 20, 2022, the SC members discussed about the future of JAK inhibition in myelofibrosis. The session was chaired by John Mascarenhas and involved an analysis from Claire Harrison, Haifa Kathrin Al-Ali, Tiziano Barbui, Jean-Jacques Kiladjian, and Stefan N. Constantinescu.

The future of JAK inhibition in myelofibrosis

Key topics of discussion included: “How to select appropriate JAK inhibitors in patients with myelofibrosis (MF)”; “What patient subsets a JAK inhibitor may capture”; and “The future of JAK inhibitors in treating myelofibrosis, and whether this type of inhibitor will exist as a single agent or in combination therapy at initiation.

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