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What are the current treatment options for intermediate/higher-risk patients with myelofibrosis?

By Oscar Williams

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John MascarenhasJohn Mascarenhas

Nov 24, 2023

Learning objective: After reading this, learners will be able to cite a new clinical development in myelofibrosis.


During the International Academy for Clinical Hematology (IACH) 2023 Congress, the MPN Hub was pleased to speak with John Mascarenhas, Icahn School of Medicine at Mount Sinai, New York, US. We asked, What are the current treatment options for intermediate/higher-risk patients with myelofibrosis?

Mascarenhas begins by outlining the goals of treatment, focusing on managing anemia in patients with a low platelet count. He then explores the option of bone marrow transplantation and discusses treatment options for patients with a high platelet count. Mascarenhas concludes by delving into emerging treatment options and potential combination therapies.

What are the current treatment options for intermediate/higher risk patients with MF?