What is the role of transplant in CNL? Key considerations about timing of transplant in CNL

During the 48th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT), the MPN Hub was pleased to speak to Bhagirathbhai Dholaria, Vanderbilt University Medical Center, Nashville, US. We asked, What is the role of transplant in CNL? What are the key considerations about timing of transplant in CNL?

Dholaria begins by discussing the difficulties in obtaining data on the effectiveness of allogeneic transplants in patients with CNL. Dholaria goes on to speak about a large-scale observational study, combining data from the CIBMTR and European transplant registry, and gives an insight into disease-free and overall survival in CNL. Finally, Dholaria touches on the role of pre-transplant therapies, such as ruxolitinib, in improving patient outcomes.