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ASH2023 abstracts: What’s hot in MPN?

Dec 4, 2023

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To help navigate the exciting content being presented at the 65th American Society of Hematology (ASH) Annual Meeting and Exposition, the MPN Hub Steering Committee members have provided their recommendations for the top abstracts to look out for in MPN.

Saturday, December 9

Sunday, December 10


Firstline treatment with ruxolitinib versus best available therapy in patients with polycythemia vera: Pre-specified interim analysis of the randomized phase 2b ruxobeat clinical trial of the German Study Group for myeloproliferative neoplasms (GSG-MPN)

Steffen Koschmieder


Transform-1: a randomized, double-blind, placebo-controlled, multicenter, international phase 3 study of navitoclax in combination with ruxolitinib versus ruxolitinib plus placebo in patients with untreated myelofibrosis

Naveen Pemmaraju


Selinexor plus ruxolitinib in JAK inhibitor (JAKi)-Naïve patients with myelofibrosis: long term follow up from XPORT-MF-034 suggestive of disease modification

Srinivas K. Tantravahi


Pelabresib in combination with ruxolitinib for Janus kinase inhibitor treatment-naïve patients with myelofibrosis: Results of the MANIFEST-2 randomized, double-blind, phase 3 study

Raajit K. Rampal


Modulation of biomarkers by BET Inhibitor, BMS-986158, including JAK2 variant allele frequency (VAF), bone marrow (BM) fibrosis, and reversal of abnormal cytokine production in intermediate- or high-risk myelofibrosis (MF)

Si Tuen Lee-Hoeflich


Efficacy and safety of fedratinib in patients with myelofibrosis previously treated with ruxolitinib: Results from the phase 3 randomized FREEDOM2 study

Claire N Harrison


Impact of symptom benefit and transfusion response on survival in myelofibrosis patients treated with pacritinib: PERSIST-2 landmark survival analysis

Helen Ajufo

Monday, December 11

ASH 2023 Top Abstracts

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