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Is pacritinib safe and efficacious for patients with MF who failed ruxolitinib?

Jan 20, 2020
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The MPN Hub were pleased to speak to Aaron Gerds, Cleveland Clinic Taussig Cancer Institute, Cleveland, US, during the 61st American Society of Hematology (ASH) meeting in Orlando, US. We asked: Could pacritinib represent a new efficacious treatment for patients with myelofibrosis who have failed ruxolitinib?

Aaron Gerds discusses the PAC203 study that evaluated the efficacy of the JAK inhibitor, pacritinib, in patients with myelofibrosis and low platelet counts, he talks about the patient characteristics, the optimal dose, safety, response rates and overall outcomes of patients. He also discusses the place of pacritinib in the treatment pathway and its effect on patient outcomes.

Is pacritinib safe and efficacious for patients with MF who failed ruxolitinib?

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