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The MPN Hub were pleased to speak to Aaron Gerds, Cleveland Clinic Taussig Cancer Institute, Cleveland, US, during the 61st American Society of Hematology (ASH) meeting in Orlando, US. We asked: Could pacritinib represent a new efficacious treatment for patients with myelofibrosis who have failed ruxolitinib?
Aaron Gerds discusses the PAC203 study that evaluated the efficacy of the JAK inhibitor, pacritinib, in patients with myelofibrosis and low platelet counts, he talks about the patient characteristics, the optimal dose, safety, response rates and overall outcomes of patients. He also discusses the place of pacritinib in the treatment pathway and its effect on patient outcomes.
Is pacritinib safe and efficacious for patients with MF who failed ruxolitinib?
Results from the PAC203 phase II trial: pacritinib dose recommendation in thrombocytopenic patients with MF
During the 61st American Society of Hematology Annual Meeting & Exposition (ASH 2019), Aaron Gerds presented an oral abstract on the results...
Editorial theme | The management of relapsed/refractory myelofibrosis: Part 2 – novel JAK inhibitors
As part of the new editorial theme on the management of relapsed or refractory myelofibrosis (R/R MF), we are now looking at the emerging therapeutic...
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