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CAR therapy
In chimeric antigen receptor (CAR) therapy, immune cells are taken from the patient, genetically modified to express the CAR construct, and then infused back into the patient. To date, most CAR therapies use engineered T cells, which express the targeted cancer cell antigen. New approaches explore the use of NK cells, allogeneic cell sources, and novel CAR constructs to optimize manufacturing and improve clinical outcomes.
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